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Centre for Genomic Regulation
The Institute
The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed by an interdisciplinary, motivated and creative scientific team which is supported both by a flexible and efficient administration and by high-end and innovative technologies.
In April 2021, the Centre for Genomic Regulation (CRG) received the renewal of the 'HR Excellence in Research' Award from the European Commission. This is a recognition of the Institute's commitment to developing an HR Strategy for Researchers, designed to bring the practices and procedures in line with the principles of the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers (Charter and Code).
The role
At the ‘Epigenetic and events in cancer’ lab we are seeking a highly motivated candidate to join our team to work on an interdisciplinary project related to validate potential therapeutic vulnerabilities in cancer. The candidate must be mastered several techniques, such as Molecular Biology (general DNA and RNA manipulation techniques including purification, cloning, mutagenesis, PCR, RT-PCR, qPCR).
About the lab
Understanding the genetic basis of cancers has been a topic of intense research, and hundreds of gene mutations have been identified that can cause carcinogenesis. However, in the past few years, increasing evidence has suggested that mutations are not the only genetic changes that lead to cancer. Indeed, perturbations of chromatin structure and of other epigenetic mechanisms can cause inappropriate gene expression and genomic instability, resulting in cellular transformation and malignant outgrowth.
Our research investigation is focused on understanding the role of several protein complexes that are involved in chromatin dynamics and metabolism, which when altered could participate in the establishment and maintenance of the aberrant silencing of tumor suppressor genes during transformation.
Whom would we like to hire?
Professional experience
Must Have
You have previous experience in the field of molecular and cellular biology
A strong publication track on the topics of gene regulation, epigenetics, and cancer
Education and training
You have accomplished you PhD course and expecting your PhD title in the next 6 months
Languages
You are proficient in English
Technical skills
You have experience with molecular biology techniques.
You have computational skills on sequencing analysis.
You have experience with tissue culture.
You have experience with biochemical techniques.
Competences
Highly developed organizational skills.
Supervising capabilities.
You are capable of working in a group, and with a high degree of work autonomy
You are highly motivated
The Offer – Working Conditions
Contract duration: Technical and scientific activities contract estimated 1 year
Estimated annual gross salary: Salary is commensurate with qualifications and consistent with our pay scales.
Target start date: 1/1/2025
We provide a highly stimulating environment with state-of-the-art infrastructures, and unique professional career development opportunities. To check out our training and development portfolio, please visit our website in the training section.
We offer and promote a diverse and inclusive environment and welcomes applicants regardless of age, disability, gender, nationality, ethnicity, religion, sexual orientation or gender identity.
The CRG is committed to reconcile a work and family life of its employees and are offering extended vacation period and the possibility to benefit from flexible working hours.
Application Procedure
All applications must include:
A motivation letter addressed to Dr Luciano Di Croce.
A complete CV including contact details.
Contact details of two referees.
All applications must be addressed to Dr Luciano Di Croce and be submitted online through the "Apply" button below.
Selection Process
Pre-selection: The pre-selection process will be based on qualifications and expertise reflected on the candidates CVS. It will be merit-based.
Interview: Preselected candidates will be interviewed by the Hiring Manager of the position and a selection panel if required.
Offer Letter: Once the successful candidate is identified the People department will send a Job Offer, specifying the start day, salary, working conditions, among other important details.
Deadline: Please submit your application by December 31, 2024.
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