Molecular Biologist

Charles River Laboratories International

Charles River Laboratories International

Bethesda, MD, USA
Posted on Dec 18, 2024

For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

Job Summary

We are looking for a Molecular Biologist to join our Insourcing Solutions team in Bethesda, MD.

The person will be responsible for the screening, identification, and sequencing of genome of transgenic and CRISPR/cas9 genome edited animals and tissue culture cells. Will represent MGGM in discussion with investigators to create GEM models.

  • Provide investigators rodent genotyping assistance. Direct individuals on the necessary steps associated with the technical duties needed to extract the DNA and run the PCR analysis for specific markers/genes.
  • Assist investigators with animal model development and give advice on creating effective GEM colonies.
  • Develop and provide investigator training presentations on creating effective gene cassettes, and related topics.
  • Familiarity with cryopreservation of sperm and embryos and in-Vitro Fertilization for long term storage of animal models.
  • Consult with all parties involved with the service as needed to set up pertinent procedures and schedules. Provide an efficient channel between the lab director, investigators and the CMB service support group.
  • Report any animal health, care, and / or well-being concerns to the appropriate facility management staff.
  • Maintain integrity of the research process, including detailed accurate record keeping and routine animal observations.
  • Report any facility infrastructure, relative to the animal care and support areas, to the appropriate facility management.
  • Ability to work flexible hours to ensure research needs and experiments are carried out to comply with appropriate timelines.
  • Perform other related duties as assigned.

Job Qualifications

  • Bachelor’s or Master’s or Ph.D. degree
  • 3-5 years of experience in a similar role
  • Strong background in molecular biology, mouse genetics, small animal handling as well as tissue culture.
  • In depth knowledge of latest techniques of CRISPR/cas9 gene editing of mammalian genome and tissue culture cells.
  • Familiarity with the production of genetically engineered mouse (GEM) models and experience of management of mouse colonies preferred
  • in-vitro Fertilization (IVF), cryopreservation and rederivation of mouse lines will be a plus.
  • The individual must be able to express verbally and in writing and have proficiency in MS Word/Access/Excel, with a background in statistical analysis.

The hourly range for this position is $44-47 USD per hour. Please note that salaries vary within the range based on factors including experience, skills, education, certifications, and location.

About Insourcing SolutionsCharles River Insourcing Solutions℠ can streamline research by delivering operational and cost efficiencies through the strategic insourcing of GMP, GLP and non-GLP research services from discovery through safety assessment. Insourcing Solutions℠ provides you with the ability to maintain control of your facility and expertise while leveraging available space.

About Charles RiverCharles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.

At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly worked on 80% of the drugs approved by the U.S. Food and Drug Administration (FDA) in the past five years.

We’re committed to providing benefits that elevate your quality of life. Based on your position these may include: bonus/incentives based on performance, 401K, paid time off, stock purchase program, Health and wellness coverage, employee and family wellbeing support programs, and work life balance flexibility.

Equal Employment OpportunityCharles River Laboratories is an Equal Opportunity Employer – all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, or national origin, veteran or disability status.

It is unlawful in some states (including Massachusetts) to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to crrecruitment_US@crl.com. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications.

For more information, please visit www.criver.com.