Research Associate, Molecular Bioanalytics

Editas Medicine

Editas Medicine

Data Science
Cambridge, MA, USA
Posted on Aug 20, 2024

At Editas, we’re driven by a collective purpose, to bring transformative and life changing therapies to people living with serious diseases with the greatest unmet needs. This fuels our drive to excel in scientific innovation, allowing us to harness the power and potential of CRISPR/Cas9 and CRISPR/Cpf1 (Cas12a) gene editing.

We believe our people are at the core of everything we do, and we’re committed to cultivating a culture where every individual feels valued and included. To do this, we strive to integrate belonging, inclusivity, diversity, and equity into every aspect of our organization.

Together, we are leading the way towards a healthier and more equitable future.

Position Summary

Editas Medicine is seeking a highly motivated and creative bioanalytical Research Associate to join our DMPK, Nonclinical Safety and Translational Sciences (DSTS) team. In this role, you would report to the Sr. Scientist of Molecular Bioanalytics and be responsible for supporting ADME, biodistribution, PK/PD and bioanalytical activities. This individual will be responsible for executing stage-appropriate molecular bioanalytical assays in support of DMPK, tox, biodistribution and PK/PD studies. The ideal candidate will have strong technical skills in PCR-based methods (ddPCR and/or TaqMan PCR), a broad understanding of drug discovery and development, and ability to work collaboratively with key partners in a matrix team structure.

Key Responsibilities:

As the Research Associate, you will be responsible for:

  • With minimal supervision, executing on routine workflows for bioanalytical method development and sample analysis using techniques such as molecular bioanalytical assays (qPCR, ddPCR) in support of non-clinical quantitative bioanalysis.
  • Independently execute and contribute to the development of PCR-based methods, sample analysis, data generation and report writing.
  • Develop nucleic acid extraction (DNA/RNA) and quantification from a broad-spectrum animal tissues.
  • Execute bioanalytical assay development strategies to characterize ADME, PK and biodistribution properties of the drug product and address key scientific questions.
  • Ensure that the data obtained is of the highest quality, timely generated
  • Write bioanalytical assay protocols, ROPs/SOPs.
  • Model behaviors of a strong technical contributor and team player.
  • Work cross-functionally within the organization.
  • Ensure compliance with electronic notebooks (ELN), high data integrity and company policies.