Company Overview: Abiologics, Inc. is a privately held, early-stage biotechnology company on a mission to make biology better through chemistry. We are pioneering the development of Synteins^TM, a transformational class of macromolecular medicines unlocked by novel synthetic and computational technologies. Abiologics is actively seeking exceptional molecular scientists who are passionate about driving chemical innovation in biotechnology. Abiologics was founded in Flagship Pioneering’s venture creation engine, where companies such as Moderna Therapeutics (NASDAQ: MRNA) and Generate Biomedicines were conceived and created.

Position Summary: Are you a highly motivated and collaborative chemist with a strong background in small molecule and/or peptide synthesis? Abiologics invites you to join our growing team and help shape the future of macromolecular medicine. As part of our early scientific team, you will contribute to building our core platform by developing breakthrough synthesis technologies that accelerate Syntein^TM construction and testing. Please apply if you are eager to develop this powerful new modality and excited to join a dynamic team!

Key Responsibilities:

• Develop and apply breakthrough chemical synthesis technologies to construct novel Synteins^TM
• Accelerate Syntein^TM prototyping and optimization through computationally-enabled structure-activity relationship (SAR) testing
• Deploy modern synthetic organic methodologies to expand the scope of Syntein^TM architecture and function
• Purify and analyze Syntein^TM macromolecular properties using modern chemical, biophysical and functional assays
• Communicate progress of work in oral and written format as part of a cross-functional team

Qualifications:

• PhD in chemistry, chemical engineering, or BS/MS with 5+ years relevant experience in biotechnology or the pharmaceutical industry
• Proficient in modern peptide synthesis, including bioconjugation, purification and analysis; capable of immediate independent laboratory work on solid- and solution-phase chemistries
• Competency in synthesis automation using modern robotics
• Working knowledge of modern synthetic organic chemistry and method development, including reaction design and troubleshooting
• Motivated to maintain a strong laboratory presence along with design, planning and execution of timebound experiments