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Lab Automation Engineer II

GeneDx Inc

GeneDx Inc

Software Engineering
Gaithersburg, MD, USA
USD 104,545-130,681 / year
Posted on Apr 25, 2025
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GeneDx (Nasdaq: WGS) delivers personalized and actionable health insights to inform diagnosis, direct treatment, and improve drug discovery. The company is uniquely positioned to accelerate the use of genomic and large-scale clinical information to enable precision medicine as the standard of care. GeneDx is at the forefront of transforming healthcare through its industry-leading exome and genome testing and interpretation services, fueled by the world’s largest, rare disease data sets. For more information, please visit www.genedx.com.

Summary

The Lab Automation Engineer II is responsible for the development, integration and testing of automated assay protocols using custom and standard microplate handling, processing, and pipetting equipment; as well as formal verification and validation testing. The incumbent should be able to develop and troubleshoot automation scripts, analyze data, draw conclusions and make recommendations on relevant data and present findings.

Job Responsibilities

  • Work within cross-functional teams to support the design and development of automated assay methods for liquid handlers and other instrumentation with limited supervision
  • Experimentally and analytically characterize hardware system and subsystem performance and capabilities
  • Design, implement and optimize software sequences for automation of assay protocols on liquid handling instrumentation
  • Participate in the development and documentation of failure modes, effects and criticality analyses with minimal supervision
  • Participate in the development of system design requirements and specifications, including interfacing with other teams to gather and refine requirements with minimal supervision
  • Develop and execute system design verification and validation test plans with minimal supervision
  • Generate and implement updates based on process improvement change orders
  • Specific duties may vary depending upon departmental requirements

Education, Experience, and Skills

  • Bachelor’s degree in Biology, Biochemistry, Engineering or a related field
  • Minimum of 5 years of experience with using, maintaining, and troubleshooting of automated assay methods required
  • Experience as a bench scientist or Labtech
  • Mastery in operation with demonstrated programming proficiency in at least one liquid handler and exposure to others. (Revvity, Hamilton, Tecan, Dynamic Devices)
  • Experience in a regulated environment preferred
  • Intermediate programmer in two or more of these languages (C#, VB.net, Javascript, Python, SQL) preferred
  • Proficiency in MS Office suite and familiarity with various IDE application for writing, editing and debugging code required
  • Demonstrated ability to reliably organize and move project tasks forward in an orderly and structured fashion without supervision
  • Proven track record of advanced analytical and problem-solving skills
  • Demonstrated ability to meet deadlines, manage processes through to completion and coordinate a high level of activity under a variety of conditions and constraints
  • Strong oral, written and interpersonal skills. Effectively communicate issues/problems and results that impact timelines, accuracy and reliability of project status. Excellent documentation skills, technical writing and presentation skills
  • Ability to suggest creative solutions while working within the confines a regulated industry
  • Proficiency working with laboratory automation such as liquid handlers, plate robotics, and other automation equipment

Physical Demands

  • This position requires the ability to communicate and exchange information, utilize equipment necessary to perform the job, and move about the office and lab.

Work Environment

  • This position is performed in R&D, light-manufacturing, and engineering office environments.

Pay Transparency, Budgeted Range
$104,545—$130,681 USD

~

Science - Minded, Patient - Focused.

At GeneDx, we create, follow, and are informed by cutting-edge science. With over 20 years of expertise in diagnosing rare disorders and diseases, and pioneering work in the identification of new disease-causing genes, our commitment to genetic disease detection, discovery, and diagnosis is based on sound science and is focused on enhancing patient care.

Experts in what matters most.

With hundreds of genetic counselors, MD/PhD scientists, and clinical and molecular genomics specialists on staff, we are the industry’s genetic testing experts and proud of it. We share the same goal as healthcare providers, patients, and families: to provide clear, accurate, and meaningful answers we all can trust.

SEQUENCING HAS THE POWER TO SOLVE DIAGNOSTIC CHALLENGES.

From sequencing to reporting and beyond, our technical and clinical experts are providing guidance every step of the way:

TECHNICAL EXPERTISE

  • High-quality testing: Our laboratory is CLIA certified and CAP accredited and most of our tests are also New York State approved.
  • Advanced detection: By interrogating genes for complex variants, we can identify the underlying causes of conditions that may otherwise be missed.

CLINICAL EXPERTISE

  • Thorough analysis: We classify variants according to our custom adaptation of the most recent guidelines. We then leverage our rich internal database for additional interpretation evidence.
  • Customized care: Our experts review all test results and write reports in a clear, concise, and personalized way. We also include information for research studies in specific clinical situations.
  • Impactful discovery: Our researchers continue working to find answers even after testing is complete. Through both internal research efforts and global collaborations, we have identified and published hundreds of new disease-gene relationships and developed novel tools for genomic data analysis. These efforts ultimately deliver more diagnostic findings to individuals.

Learn more About Us here.

Our Culture

At GeneDx, we are dedicated to cultivating an environment where creativity and innovation thrive. We believe in the power of community and collaboration, where diverse perspectives are embraced, and every voice contributes to our shared success. Our team is a vibrant mix of professionals who challenge and support each other in equal measure, fostering growth both personally and professionally. When you join us, you're not just taking on a job—you're joining a movement. A movement that champions curiosity, embraces change, and believes in making an impact, one patient at a time. Cultural principles we live by:

  • Be bold in our vision & brave in our execution.
  • Communicate directly, with empathy.
  • Do what we say we're going to do.
  • Be adaptable to change.
  • Operate with a bias for action.

Benefits include:

  • Paid Time Off (PTO)
  • Health, Dental, Vision and Life insurance
  • 401k Retirement Savings Plan
  • Employee Discounts
  • Voluntary benefits

GeneDx is an Equal Opportunity Employer.

All privacy policy information can be found here.

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