Senior Scientist



Upper Providence Township, PA, USA
Posted on Sunday, May 19, 2024

GSK has an immediate opening for a Senior Scientist for mass spectrometry and protein characterization in Collegeville, PA. The candidate will primarily be responsible for conducting mass spec-based experiments (e.g. LC-MS and LC-MS/MS) for the characterization of therapeutic proteins. The candidate may be expected to develop other analytical and/or biochemical methods to further understand the structure-function relationship of proteins, while supporting biopharmaceutical development from FTIH through commercial.

The mass spec group is well equipped with modern instrumentation including Thermo Eclipse Tribrid, Thermo Exploris 480, Thermo Exploris 240, Thermo Exploris MX, Thermo Fusion Tribrid, Waters Synapt G2-S, Waters Xevo G2-XS, Agilent 6490 QQQ, ZipChip, Nano-LC, UHPLC and many other supporting instrumentation and associated data analysis software packages.

Why you?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

  • B.S. with 4+ years of experience or M.S. with at least 2 years of experience in biotech or pharmaceutical industry

  • Working knowledge of protein and carbohydrate structures

  • Experience with operating and maintaining mass spectrometers and UHPLC instruments

  • Experience with software tools for processing protein mass spectrometry data

Preferred Qualifications:

If you have any of the following characteristics, it would be a plus:

  • Experience in protein characterization using mass spectrometry, including top-down/middle-down and bottom-up LC-MS approaches

  • Experience with biopharmaceuticals and their process development

  • Knowledge of GxP requirements

  • Experience in various separation techniques such as CE, SEC, IEX and HPLC/UHPLC

  • Experience with small molecule structure elucidation

  • Good technical writing skills for documentation, experience in regulatory documentation authoring

  • Experience with proteomics or metabolomics

  • Experience with oligonucleotide analysis

  • Experience with quantitative assay development

  • Ability to collaborate and communicate well with others in and across matrix teams

  • Thorough operational knowledge of laboratory equipment and laboratory systems

  • Strong communication skills, both written and verbal


Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

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