Hologic (NASDAQ: HOLX) is an innovative medical technology company whose purpose is to enable healthier lives everywhere, every day. While we discover and develop groundbreaking products and services that benefit everyone, we are especially passionate about those that advance women’s health and well-being. This allows us to be a company that prospers, grows and empowers women to experience healthier lives.

We are seeking an experienced Scientist responsible for supporting the operations of the Oligonucleotide Core Center, providing oligonucleotide synthesis, purification, and analysis for the R&D diagnostics business unit of Hologic, which is located in San Diego, California.

Duties and Responsibilities

This position will require automated synthesis of oligonucleotides, purification of oligonucleotides by chromatographic techniques and characterization of oligonucleotides by a variety of physicochemical techniques and conjugation of oligonucleotides by a variety of methods. The candidate will also participate in basic research projects exploiting novel properties of oligonucleotides in diagnostic assays.

The candidate will be responsible for a significant portion of a complex project or an entire less complex project or multiple less complex projects. The ideal candidate should understand the scope of the overall project in the scope of corporate strategy. They may manage 2 or more personnel and may represent R&D on a Core Team for a product development project.

The candidate is expected to present work internally or at scientific conferences or write scientific papers. They are required to collaborate and communicate effectively with junior level employees, peers and cross-functional teams across all levels of the organization.

• Conduct oligonucleotide analysis using LCMS, MALDI, UV/VIS, and HPLC/UPLC techniques. Evaluate and identify impurities, degradation products, and synthesis by-products. Establish analytical protocols and support implementation of these protocols.
• Perform automated oligonucleotide synthesis, deprotection and purification via standard phosphoramidite chemistry and chromatographic purification techniques.
• Lead and execute complex experiments, including providing guidance and direction on experimental design, analysis and interpretation of data, communication of results, and design of follow-up experiments. Responsible for subproject or project goals and deliverables.
• Interact with peers and supervisors, both within the team as well as with other teams, to provide experimental summaries, design input, and ancillary team functions.
• Maintain clearly written experimental records in both written and electronic formats.
• Familiar with standard software tools utilized in instrument control, data analysis, and reporting results.
• Familiar with additional techniques in biomolecular analysis and general analytical techniques, including FTIR, CE, fluorimetry, Karl-Fischer titration, NMR, etc.

Required Education and Experience

• A degree in chemistry, biochemistry or biology is required
• A minimum of 3 - 5 years of industry experience is preferred, specifically in oligonucleotide synthesis and purification; large-scale oligonucleotide synthesis experience desired; experience working in regulated environments desired
• 6-8 years laboratory experience post-M.S. without thesis; 5-7 years laboratory experience post M.S. with thesis.
• Ph.D. with no post-doctoral research experience or 4-6 years industrial experience; Ph.D. with post-doctoral research experience and 3-5 years industrial experience.

The annualized base salary range for this role is $95,800 to $149,900 and is bonus eligible. Final compensation packages will ultimately depend on factors including relevant experience, skillset, knowledge, geography, education, business needs and market demand.

Why Hologic?

We are committed to making Hologic the company where top talent comes to grow. For you to succeed, we want to enable you with the tools and knowledge required and so we provide comprehensive training when you join as well as continued development and training throughout your career.

If you have the right skills and experience, apply today!

#LI-RF1 #Mid-level

Agency and Third Party Recruiter Notice:

Agencies that submit a resume to Hologic must have a current executed Hologic Agency Agreement executed by a member of the Human Resource Department. In addition Agencies may only submit candidates to positions for which they have been invited to do so by a Hologic Recruiter. All resumes must be sent to the Hologic Recruiter under these terms or they will not be considered.

Hologic, Inc. is proud to be an Equal Opportunity Employer inclusive of disability and veterans.