Work Schedule

12 hr shift/nights

Environmental Conditions

Able to lift 40 lbs. without assistance, Adherence to all Good Manufacturing Practices (GMP) Safety Standards, Cleanroom: no hair products, jewelry, makeup, nail polish, perfume, exposed piercings, facial hair etc... allowed, Cold Room/Freezers -22degreesF/-6degrees C, Loud Noises (Equipment/Machinery), No contact lens allowed; prescriptive glasses will be provided, Some degree of PPE (Personal Protective Equipment) required (safety glasses, gowning, gloves, lab coat, ear plugs etc.), Standing for full shift, Will work with hazardous/toxic materials

Job Description

Downstream Processing Supervisor (Band 6)

Location: St. Louis, MO | Drug Substance Division (Biologics)
Work Schedule: Nights, 12-hour shifts (2, 2, 3 rotation)
Shift Differential: 15%

Discover Impactful Work:
Join Thermo Fisher Scientific as a Downstream Processing Supervisor and play a pivotal role in the success and oversight of downstream manufacturing processes. Be responsible for conducting a variety of functions related to Downstream Biopharmaceutical Manufacturing, including large scale chromatography, viral inactivation, viral filtration, ultrafiltration, diafiltration, and aseptic filling of bulk drug substances.

Explore an outstanding chance as a Supervisor in Formulation Manufacturing - Nights with Thermo Fisher Scientific Inc. Join our team committed to excellence and teamwork.

Responsibilities

• Supervise and lead night shift operations in the formulation manufacturing department, ensuring adherence to cGMP standards.
• Coordinate flawless execution of manufacturing batch records, work instructions, and SOPs.
• Strictly monitor and maintain suite, supplies, equipment, logbooks, and data integrity.
• Proactively identify and resolve supply and raw material deficiencies, scheduling conflicts, and process deviations.
• Conduct root cause analysis and drive continuous improvement initiatives.
• Lead and facilitate daily huddles and shift exchanges, acting as a liaison and Subject Matter Expert.
• Provide mentorship and training to team members, encouraging a collaborative and high-performance culture.
• Ensure compliance with all safety regulations and promote safe work habits.

Requirements

• HS Diploma/GED required; Bachelor’s degree in Biology, Chemistry, Engineering, or related field preferred.
• 5-9 years of relevant work experience, with at least 2 years in a supervisory role, preferably in the pharmaceutical industry.
• Proven knowledge of cGMP practices, aseptic techniques, and chemical concepts.
• Strong critical thinking, problem-solving capabilities, and effective communication skills.
• Ability to multi-task, work independently, and collaborate within a team.
• Physical capability to adhere to cleanroom gowning requirements and lift a minimum of 25 lbs independently.

Keys to Success

• Diligent and results-oriented with outstanding organizational skills.
• Efficient in MS Office and capable of critical evaluation of processes.
• Demonstrated ability to foster cross-functional relationships and improve team performance.
• Dedication to maintaining a safe and compliant work environment.

Join Thermo Fisher Scientific Inc. and contribute to making the world healthier, cleaner, and safer. Apply today and be part of our world-class team!