Principle Scientist - CPAD

Pfizer

Pfizer

Chennai, Tamil Nadu, India
Posted on Dec 27, 2024
  • State of the art knowledge of modern synthetic methodology, including aspects of asymmetric synthesis, green chemistry, catalysis, and physical organic chemistry as it relates to reaction mechanism is expected.
  • Contemporary knowledge of drug development, the pharmaceutical industry, and fundamental principles of process development from a laboratory and manufacturing perspective.
  • Strong track record of successful delivery of projects, using sound scientific analysis and judgment to advance programs
  • Good interpersonal skills
  • Experience of leading small teams of 5-8 chemists, mentoring and directing other colleagues.
  • Excellent oral and written communication skills, including the ability to maintain an accurate scientific notebook, and draft concise emails, written reports, publications, synthesis information packages and related documents
  • Rational, innovative and creative approach to problem solving.
  • Job location: Onsite, Chennai
  • Lead a group of 5-8 process chemists at an external partner located in India to deliver phase-appropriates processes and vendor synthetic information packages (VSIPs) for Pfizer’s Drug-Linker portfolio.
  • Use extensive technical knowledge and experience in state-of-the-art organic and process chemistry to develop safe, sustainable, robust, cost-efficient, and phase-appropriate process that are aligned with internal business needs.
  • Develop strategic plan to develop and implement purification and separation capabilities at the external partner that is driven by drug linkers portfolio needs with internal stakeholders.
  • Work collaboratively and effectively, building and leading high performing teams
  • Ensure accurate and timely documentation of experimental work, and clear and concise presentation of work to stakeholders both internally and externally.
  • Co-ordinate work with other functions (Process safety, engineering, analytical)/ departments to achieve project objectives.
  • Build a strong interface and network with Pfizer’s Chemical Process and Analytical Development group (Global Chemical Research and Development) and keep up to date with synthetic and technology advancements.
  • Support in designing and refining workflows and metrics.
  • Look for opportunities to align, share and implement best practices.
  • Contribute to the development of a strong scientific, process chemistry, safety and quality culture within the chemistry labs.
  • Master’s degree in Chemistry, Chemical Engineering or a related field and 10+ years of experience in process chemistry research and development towards New Chemical Entities (APIs) or fine chemicals
  • or

  • PhD in Organic Chemistry or a related field with 6+ years of experience in process chemistry research and development towards New Chemical Entities (APIs) or fine chemicals
  • Develop state of the art purification strategies and capabilities for complex synthetic molecules such as Drug-Linkers.
  • Plan the scientific direction of projects by providing high quality experimental planning, evaluation and characterization of chromatography purification and synthetic processes.


Work Location: Onsite, Pfizer Chennai

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.

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