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Takeda Pharmaceutical Company Limited
At Takeda, we strive to provide transformational opportunities for every member of our team, and we empower our people to take charge of their futures. In an environment that fosters lifelong learning and a growth mindset, you’ll have the support you need to thrive — at work and beyond.
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At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on four therapeutic areas and other targeted investments, we push the boundaries of what is possible in order to bring life-changing therapies to patients worldwide.
Join Takeda as a Viral Vector Stable Cell Line Development Lead where you will be the subject matter expert overseeing all aspects of viral vector stable cell line development, including cloning, screening, characterization, stability, and productivity evaluation. You will leverage your expertise to establish GMP-ready stable Viral Vector producer cell lines, from concept initiation to delivering top-performing clones for Takeda’s Cell Therapy pipeline. A key responsibility will be to manage cross-functional collaborations across CMC, Strategy, and Research teams to ensure timely delivery of robust stable producer clones for Takeda’s pipeline.
Serve as the subject matter expert and lead for all aspects of viral vector stable cell line development, including cloning, screening, characterization, stability, and productivity evaluation.
Partner with the Viral vector strategy team for the development and execution of strategy for generation of stable Viral vector producer cell lines for Gamma Retrovirus for various Cell Therapy programs.
Work in close collaboration with Upstream & Downstream Viral Vector Process development teams to design, develop and optimize robust viral production processes for stable producer cell lines.
Apply your expertise in genomics, transcriptomics and analytical assays such as Viral Vector titration assay, DNA sequencing, PCR, Southern/Northern blots, in collaboration with the Analytical Development team for comprehensive cell line characterization and optimization.
Ensure compliance with regulatory requirements and guidelines for stable cell line development and viral vector production, maintaining adherence to industry standards.
Leverage your proven experience in establishing and maintaining cell banks (RCB, MCB, WCB) to support consistent and reliable cell line development.
Utilize your familiarity with automated systems to conduct high-throughput screening of cell lines and optimize experimental conditions.
Ensure optimal alignment and coordination with cross-functional matrixed teams.
Work closely with senior team leaders and cross-functional teams and provide scientific leadership and technical recommendations.
Support IND enabling studies and filing related document preparation. Draft technical documents, such as SOPs and study reports.
Lead cross-functional teams effectively, driving collaboration across disciplines and delivering high-quality results to advance Takeda’s Cell Therapy pipeline.
Collaborate with data and digital teams to develop fully digitalized data capture and tracking.
Serves as a technical mentor for junior staff, providing guidance and training in laboratory technology and leverages domain expertise to support their development and enhance functional capabilities.
Preparation and presentation comprehensive technical or project reports and formal presentations to both internal and external audiences.
PhD degree in a scientific discipline with 3+ years experience or MS with 8+ years experience, or BS with 10+ years experience in Virology, Molecular biology, Immunology, Bioengineering, or related scientific disciplines with relevant experience.
3+ years of industry experience in Cell line development is required.
Previous experience in Cell Therapy or related field is highly preferred.
At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.
Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.
Takeda Compensation and Benefits Summary
We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.
For Location:
Boston, MAU.S. Base Salary Range:
133,000.00 - 209,000.00The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.
U.S. based employees may be eligible for short-term and/or long-termincentives. U.S.based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S.based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.
EEO Statement
Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.
Job Exempt
YesOur team at Takeda is tackling some of the most challenging problems in drug discovery and development. As the newest member of our Research team, you’ll conduct purposeful, meaningful work on groundbreaking modalities that may lead to breakthrough drugs.
With our deep investment in next-generation technologies, you’ll have the resources and support to do your best work. As a part of our team, you’ll connect with brilliant minds inside and outside of Takeda. We are committed to collaborating with academia and emerging biotech companies to expand our reach and impact in cell therapy, gene therapy and data sciences.
Our team’s wide-ranging expertise includes medicinal chemistry, genomics datasets, immunofluorescence, high content imaging, flow cytometry, transcriptional profiling, multi-step synthesis, multimodal genetics, pharmacokinetics and much more. Whatever area inspires you, your work will support the progression of an innovative, industry-leading discovery pipeline and make an impact that matters to patients and society.
A career in Research at Takeda will give you everything you need to succeed professionally — and make a difference to patients, people and the planet.
Design and carry out experiments
Manage multiple projects
Document data
Mentor other scientists
Along with incredibly passionate colleagues, there’s a clear commitment to invest in the best facilities and the right equipment needed to successfully perform world-class science.
Christina Alves - Head of Biotherapeutics Process Development
Our internal research capabilities and external partnerships contribute to an R&D engine that has produced exciting new molecular entities (NMEs) across our core Therapeutic Areas. Check out our pipeline and see how we’ll continue delivering a steady stream of next-generation therapies.
Our values of Takeda-ism are Integrity, Fairness, Honesty and Perseverance, with Integrity as the core. These are brought to life through actions based on Patient, Trust, Reputation and Business, in that order.
Our belief in putting people first extends beyond our patients — it includes their families and communities, as well as our Takeda colleagues and their families.
We are committed to embracing our differences, valuing different perspectives, and fostering a culture of respect, inclusiveness and empowerment.
Our embedded Diversity, Equity & Inclusion (DE&I) strategy enables us to attract and retain exceptional talent, drives innovation, and helps address systemic inequalities in our communities.
Integrity
Fairness
Honesty
Perseverance
Inclusion
Here, you will feel welcomed, respected, and valued as a vital contributor to our global team.Collaboration
A strong, borderless team, we strive together towards our priorities and inspiring mission.Innovation
Bold initiatives, continuous improvement, and creativity are at the heart of how we bring scientific breakthroughs from the lab to patients.Top Workplace
Recognized for our culture and way of working, we’re one of only 17 companies to receive Top Global Employer® status for 2024.Work-Life
Our people-first mission extends beyond patients to include their families, communities, and our own Takeda family.Empowerment
Through trust and respect, you will have genuine support from leaders, managers, and colleagues to do your best work.Patient
Responsibly translate science into highly innovative medicines and accelerate access to improve lives worldwide.
People
Create an exceptional people experience.
Planet
Protect our planet.
Data & Digital
Transform Takeda into the most trusted, data-driven, outcomes-based biopharmaceutical company.
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